Fit-for-Purpose COA Development: 25 years developing, modifying and validating PROs in more than 60 therapeutic categories. LEARN MORE

QualityMetric is now an IQVIA Business: click here for more information on the IQVIA COAs available for licensing

Translation Services: 25 years developing linguistically validated translations of COAs, CRFs, protocols, manuals, etc… READ MORE

QualityMetric By The Numbers: 53,000,000+ Global Survey administrations, 48,000+ Peer-reviewed articles across 100+ conditions, 200+ Language translations by mode of administrations, 100+ Condition-Specific, Country-Specific, and Insurance Claims Benchmarks General Population Norms. Which survey should you use? SEE OUR SUITE OF PRO SURVEYS

ePRO & EDC Integration: Seamless integration for optimal efficiencies using Web Service Application Programming Interface (API), Single Sign-on Access (SSO) or Electronic-Friendly Survey Administration. FIND OUT HOW

HIT-6 NEW PROS IN ONCOLOGY GUIDE

QM PROs can help capture slowed decline in physical functioning and well-being. Learn how to illuminate the impact of cancer treatments and therapies using PRO measures in a free oncology-focused guide.

Read the Guide

The Transthyretin Amyloidosis Quality of Life Questionnaire (ATTR-QOL)

Measure health-related quality of life (HRQoL) in patients living with transthyretin amyloidosis (ATTR).

ATTR is a rare disease that primarily affects the heart and nervous system. The ATTR-QOL is a disease-specific patient-reported outcome (PRO) measure that helps researchers collect information on the patient experience of this rare disease, including symptoms and the ways in which those symptoms impact HRQoL. This PRO measure is appropriate for all types of ATTR, including hereditary (hATTR, ATTRv) and wild-type (ATTRwt).

Contact us for a review of our capabilities by phone at (800) 572-9394 or by filling out the form. For academic organizations click here.

BACK

Select the organization that best describes your company:

Survey License Application

Please answer the following questions and we will be in touch regarding your license

Thank you for your request.

QualityMetric is reviewing your application and will get back to you shortly with approval to move forward with a license to administer, collect, score, and interpret the data for your project/study.

Next steps:

If you have started administering the survey, please email a copy of the survey being administered to [email protected]. We will QA the form for any changes that may affect the scoring and interpretation of the data collected. (Fees may apply).

If you are applying for a student license, please email a copy of your student ID to [email protected].

An Important Instrument for the ATTR Community

The Amyloidosis Research Consortium (ARC) spearheaded the effort to develop the ATTR-QOL in response to the needs and requests of the ATTR research community. QualityMetric provided the technical expertise to develop and evaluate the measure, collaborating with experts, clinicians, researchers, patients, patient advocates and drug developers and ensuring its alignment with current best practices in COA measure development. The resulting questionnaire provides researchers and clinicians with a standard measure for assessing the patient experience of ATTR; it can be used to inform treatment plans, better understand the natural history of this rare disease or evaluate treatment efficacy or effectiveness.

The ATTR-QOL has two primary modules that assess symptoms and impacts and a third, optional module that provides a standardized way of assessing ATTR type and 11 common comorbidities. It was developed to be used in clinical trials and research settings as well as in clinical practices and is unique in that it includes questions relevant to both primary manifestations of ATTR—polyneuropathy and cardiomyopathy—making it relevant across ATTR types (hATTR/ATTRv and ATTRwt).

Historically, research in this rare disease relied on a patchwork of existing questionnaires created for other conditions with similar symptomatologies, with some focused on the heart and others focused on neuropathies. The disease-specific ATTR-QOL eliminates the need for researchers to score and interpret multiple PRO surveys created for other conditions, reduces the likelihood of missing important symptoms and impacts and lessens the reporting burden on patients, who can complete one questionnaire instead of several.

Related Research

The Transthyretin Amyloidosis – Quality of Life (ATTR-QOL) Questionnaire: Development of a Conceptual Model and Disease-Specific Patient-Reported Outcome Measure
Patient Related Outcome Measures

Read Article

Advancing Amyloidosis: A Research Roadmap
Amyloidosis Research Consortium

Read Article

Patient and Family Experience with Transthyretin Amyloid Cardiomyopathy (ATTR-CM) and Polyneuropathy (ATTR-PN) Amyloidosis: Results of Two Focus Groups
Orphanet Journal of Rare Diseases

Read Article

Patient-Reported Burder of Hereditary Transthyretin Amyloidosis on Functioning and Well-Being.
Journal of Patient Reported Outcomes

Read Article
stopwatch icon
Completion Time:
10–20 minutes
people icon
Administered to:
Adults aged 18 and older
arrow around circle
Recall periods:
1-month
Speech Bubble
Translations:
23

Interpretation & Insights

Combining our eCOA Platform with research expertise, our consultants help your teams develop, validate, implement and analyze PROs with a custom approach. Our services ensure you gain the most meaningful insights on patient-reported data.

Consulting Support
BURDEN OF DISEASE
ANALYSIS
TREATMENT EFFICACY
ANALYSIS
NORM-BASED
INTERPRETATION OF
TREATMENT EFFECTS
CATEGORICAL CHANGE
ANALYSIS: TREATMENT
RESPONDERS
CRITERION-BASED
INTERPRETATION OF
CHANGE SCORES
CONTENT-BASED
INTERPRETATION
DEPRESSION
SCREENING
ADVANCED PREDICTIVE INTERPRETATION

  • Medical Expenditure

  • Healthcare Utilization

  • Productivity

  • Health Utility

  • Future Hospitalization

Translations Available by Modes of Administration

Please select a mode for a full list of translations available within that mode.
If you need a version in a language that is not listed, consult with our translation team to determine a cost estimate and timeline that fits to your project needs.

TRANSLATION SERVICES
computer icon
COMPUTER
tablet icon
TABLET
smartphone icon
SMARTPHONE
paper icon
INTERVIEWER SCRIPT
multiple papers icon
PAPER FORM
computer app
DCT COMPATIBLE

There’s Strength in QualityMetric’s Numbers.

We are recognized leaders in patient-reported outcomes (PRO) and clinical outcomes assessment (COA) measurement solutions, working with the top healthcare and life science companies to better understand function health and well-being.

COA Platform for Data Collection, Scoring & Interpretation

DESKTOP SOFTWARE

Our proprietary COA desktop software, which provides the ability to collect, score and interpret data for your study or program.
Learn More

ELECTRONIC DATA CAPTURE

A customizable, cloud-based data collection and reporting portal for capturing data from patients or clinicians securely and accurately.
Learn More

ANALYTICS MODULE

Our advanced reporting feature, built to seamlessly convert patient-reported data into reports with actionable insights
Learn More

SCORING & INTERPRETATION

Standardized solutions for scoring datasets with absolute accuracy and identifying errors that may impact interpretation of results.
Learn More

.funny{ display:none !important; }